EHMTI-0154. Brainstem mechanisms of trigeminal nociception: an fMRI study at 3T
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چکیده
منابع مشابه
Physiological brainstem mechanisms of trigeminal nociception: An fMRI study at 3T
The brainstem is a major site of processing and modulation of nociceptive input and plays a key role in the pathophysiology of various headache disorders. However, human imaging studies on brainstem function following trigeminal nociceptive stimulation are scarce as brainstem specific imaging approaches have to address multiple challenges such as magnetic field inhomogeneities and an enhanced l...
متن کاملMolecular mechanisms of trigeminal nociception and sensation of pungency.
One characteristic shared by many nociceptive neurons is sensitivity to capsaicin, the main pungent ingredient of ‘hot’ chili peppers (Szallasi and Blumberg, 1999). When a capsaicin receptor was isolated using a Ca2+-imaging-based expression cloning method, it was designated vanilloid receptor subtype 1 (VR1) because a vanilloid moiety constitutes an essential chemical component of capsaicin (C...
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OBJECTIVE This study examined modulation of trigeminal pain/nociception by 2 supraspinal mechanisms: emotional controls of nociception and diffuse noxious inhibitory controls. BACKGROUND Prior research suggests emotional picture viewing (emotional controls) and tonic noxious stimuli (diffuse noxious inhibitory controls) engage supraspinal mechanisms to modulate pain and nociceptive processes....
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Sci./Am.Physiol. Soc.. ESSN: 1548-9221. Visit our website at http://www.the-aps.org/. American Physiological Society, 9650 Rockville Pike, Bethesda MD 20814-3991. © 2000 Int. Union Physiol. the physiological developments. It is published bimonthly in February, April, June, August, October, and December by (formerly published as News in Physiological Science) publishes brief review articles on m...
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BACKGROUND The trigeminal subnucleus caudalis (Vc) plays a critical role in transmission and modulation of nociceptive afferent inputs, and exhibits a similar layer construction to the spinal dorsal horn. However, afferent inputs enter the brainstem and project to a separately located nucleus. It has previously been difficult to record responses of the Vc to afferent fiber activation in a brain...
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ژورنال
عنوان ژورنال: The Journal of Headache and Pain
سال: 2014
ISSN: 1129-2369,1129-2377
DOI: 10.1186/1129-2377-15-s1-e33